InterPro : IPR016357

Name  Transferrin Short Name  Transferrin
Type  Family Description  Transferrins are eukaryotic iron-binding glycoproteins with the ability to bind ferric iron with high affinity in the cleft of each of two homologous lobes. They control the level of free iron in biological fluids []. Members of the family include blood serotransferrin (siderophilin), milk lactotransferrin (lactoferrin), egg white ovotransferrin (conalbumin) and membrane-associated melanotransferrin. Family members that do no bind iron have also been discovered, including inhibitor of carbonic anhydrase (ICA), which strongly binds to and inhibits certain isoforms of carbonic anhydrase [].

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



2 Child Features

Id Name Short Name Type
IPR029773 Melanotransferrin MTF Family
IPR029785 Inhibitor of carbonic anhydrase ICA Family

1 Contains

Id Name Short Name Type
IPR018195 Transferrin family, iron binding site Transferrin_Fe_BS Binding_site

0 Found In

0 Parent Features

2 Publications

First Author Title Year Journal Volume Pages
Crichton RR Iron transport and storage. 1987 Eur J Biochem 164 485-506
Eckenroth BE The structure and evolution of the murine inhibitor of carbonic anhydrase: a member of the transferrin superfamily. 2010 Protein Sci 19 1616-26

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)