InterPro : IPR005714

Name  ATPase, type III secretion system, FliI/YscN Short Name  ATPase_T3SS_FliI/YscN
Type  Family Description  Proteins in this entry show extensive homology to the ATP synthase F1 beta subunit, and are involved in type III protein secretion. They fall into the two separate functional groups outlined below.The first group, exemplified by the Salmonella typhimuriumFliI protein (), is needed for flagellar assembly. Most structural components of the bacterial flagellum are translocated through the central channel of the growing flagellar structure by the type III flagellar protein-export apparatus in an ATPase-driven manner, to be assembled at the growing end. FliI is the ATPase that couples ATP hydrolysis to the translocation reaction [, ].The second group couples ATP hydrolysis to protein translocation in non-flagellar type III secretion systems. Often these systems are involved in virulence and pathogenicity. YscN () from pathogenic Yersinia species, for example, energises the injection of antihost factors directly into eukaryotic cells, thus overcoming host defences [].

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



4 Child Features

Id Name Short Name Type
IPR013380 ATPase, type III secretion system, H+-transporting ATPase_T3SS_H-transp Family
IPR022425 Flagellar export ATPase FliI, clade 2 FliI_clade2 Family
IPR020005 Flagellar export ATPase FliI, clade 1 FliI_clade1 Family
IPR022426 Flagellum-specific ATP synthase FliI, clade 3 FliI_clade3 Family

3 Contains

Id Name Short Name Type
IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain ATPase_F1_a/bsu_N Domain
IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain ATPase_F1/V1/A1_a/bsu_nucl-bd Domain
IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site ATPase_a/bsu_AS Active_site

0 Found In

0 Parent Features

3 Publications

First Author Title Year Journal Volume Pages
Minamino T Self-assembly and type III protein export of the bacterial flagellum. 2004 J Mol Microbiol Biotechnol 7 5-17
Minamino T Crystallization and preliminary X-ray analysis of Salmonella FliI, the ATPase component of the type III flagellar protein-export apparatus. 2006 Acta Crystallogr Sect F Struct Biol Cryst Commun 62 973-5
Blaylock B Characterization of the Yersinia enterocolitica type III secretion ATPase YscN and its regulator, YscL. 2006 J Bacteriol 188 3525-34

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)