InterPro : IPR006398

Name  2-hydroxy-3-oxopropionate reductase Short Name  Tartro_sem_red
Type  Family Description  These sequences represent 2-hydroxy-3-oxopropionate reductase (), also called tartronate semialdehyde reductase. It follows glyoxylate carboligase and precedes glycerate kinase in D-glycerate pathway of glyoxylate degradation. The eventual product, 3-phosphoglycerate, is an intermediate of glycolysis and is readily metabolized. Tartronic semialdehyde, the substrate of this enzyme, may also come from other pathways, such as D-glucarate catabolism [, ].

Sequence Features

GO Displayer


InterPro protein domain ID --> Contigs



0 Child Features

3 Contains

Id Name Short Name Type
IPR006115 6-phosphogluconate dehydrogenase, NADP-binding 6PGDH_NADP-bd Domain
IPR013328 Dehydrogenase, multihelical DH_multihelical Domain
IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site 3-OH-isobutyrate_DH-rel_CS Conserved_site

0 Found In

1 Parent Features

Id Name Short Name Type
IPR015815 Hydroxy monocarboxylic acid anion dehydrogenase, HIBADH-type HIBADH-type Family

2 Publications

First Author Title Year Journal Volume Pages
Monterrubio R A common regulator for the operons encoding the enzymes involved in D-galactarate, D-glucarate, and D-glycerate utilization in Escherichia coli. 2000 J Bacteriol 182 2672-4
Cusa E Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli. 1999 J Bacteriol 181 7479-84

To cite PlanMine, please refer to the following publication:

Rozanski, A., Moon, H., Brandl, H., Martín-Durán, J. M., Grohme, M., Hüttner, K., Bartscherer, K., Henry, I., & Rink, J. C.
PlanMine 3.0—improvements to a mineable resource of flatworm biology and biodiversity
Nucleic Acids Research, gky1070. doi:10.1093/nar/gky1070 (2018)